Berenson-Allen Center for Noninvasive Brain Stimulation (CNBS)
Optimizing and applying noninvasive brain stimulation to health care and research

Faculty

Felipe Fregni, MD, PhD
Principal Investigator

I have been in the CNBS since March of 2003. I completed my medical training, neurology residency and PhD in Medical Science in Sao Paulo (Brazil) at University of Sao Paulo. In Boston, I pursued two master programs in clinical research - Scholars in Clinical Science Program (a competitive two-year post-graduate program from Harvard Medical School) and a master in public health (MPH) - Clinical Effectiveness - from Harvard School of Public Health. Now I am an Assistant Professor of Neurology at Harvard Medical School and the Director of the Clinical Trials Network at the CNBS.

Research Interests / Research Focus

I have designed my education and training aiming for a career as a clinician-scientist. The focus of my research has largely been centered upon developing methods of non-invasive brain stimulation such as repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS) as potential treatment tools for certain neurological and psychiatric disorders.

Relevant Publications

1. Fregni F, Simon DK, Wu A, Pascual-Leone A. Non-invasive brain stimulation for Parkinson's disease: a systematic review and meta-analysis of the literature.J Neurol Neurosurg Psychiatry. 2005 Dec;76(12):1614-23.

2. Fregni F, Dasilva D, Potvin K, Ramos-Estebanez C, Cohen D, Pascual-Leone A, Freedman SD. Treatment of chronic visceral pain with brain stimulation. Ann Neurol. 2005 Dec;58(6):971-972.

3. Fregni F, Boggio PS, Mansur CG, Wagner T, Ferreira MJ, Lima MC, Rigonatt SP, Marcolin MA, Freedman SD, Nitsche MA, Pascual-Leone A. Transcranial direct current stimulation of the unaffected hemisphere in stroke patients. Neuroreport. 2005 Sep 28;16(14):1551-1555.

4. Fregni F, Santos CM, Myczkowski ML, Rigolino R, Gallucci-Neto J, Barbosa ER,Valente KD, Pascual-Leone A, Marcolin MA. Repetitive transcranial magnetic stimulation is as effective as fluoxetine in the treatment of depression in patients with Parkinson's disease. J Neurol Neurosurg Psychiatry. 2004; 75(8):1171-4.

5. Fregni F, Marcolin MA, Myczkowski ML, Amiaz R, Hasey G, Rumi D, et al. Predictors of antidepressant response in clinical trials of transcranial magnetic stimulation. Int J Neuropsychopharmacol 2006; in press.

6. Mansur CG*, Fregni F*, Boggio PS, Riberto M, Gallucci-neto J, Santos CM, Rigonatti SP, Marcolin MA, Pascual-Leone A, Marcolin MA. A sham-stimulation controlled trial of rTMS of the unaffected hemisphere in stroke patients. Neurology. 2005 May 24;64(10):1802-4. *Equally contributing authors.

7. Fregni F, Thome-Souza S, Nitsche M, Freedman SF, Pascual-Leone A, Valente K. A controlled clinical trial of cathodal DC polarization in patients with refractory epilepsy. Epilepsia. 2006; in press.

Link to NIH Formatted CV

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