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Javier Cudeiro, MD, PhD

Javier Cudeiro, MD, PhD
Visiting Scientist

Education History:

M.D., Faculty of Medicine. Honours degree in Medicine, University of Santiago de Compostela, Spain
Ph.D., Medicine, University of Santiago de Compostela, Spain
MS, Neuroendocrinology, University of Santiago de Compostela, Spain
MS, Physiology and Medicine of Sleep, University Pablo de Olavide, Spain

Research Interests:

Javier has an interest in both basic, and translational research.

1. Basic research: Results obtained in our laboratory first showed that nitric oxide (NO) plays a fundamental role in vision, and demonstrated that, in the thalamus, NO regulates the transfer of information on route to the primary visual cortex. Furthermore, it has been demonstrated that NO also plays a key role in the homeostatic control of sleep and arousal. Currently, Javier is most focused on the feedback mechanisms operating in the early visual system (mainly LGN-V1). Javier uses a range of different techniques, from single unit recording and iontophoresis to spectrophotometry and TMS.

2. Translational research: Our laboratory has shown that Parkinsonian patients often exhibit a strong dependence on external sensory cues (either visual or acoustic). Patients can generate a normal gait pattern in the presence of adequate regulatory sensory stimulation. Subsequently, our lab has developed and patented a small, hand-held device, comprising a base unit, which produces and sends auditory and visual information wirelessly to earphones and goggles worn by the patient. To date, the best results have been obtained with patients prone to “freezing". Javier is interested on Virtual Reality as a tool for Neurorehabilitation.

Some Key Publications:

  1. Robles-Garcia V, Arias P, Sanmartin G, Espinosa N, Flores J, Grieve KL, Cudeiro J. Motor facilitation during real-time movement imitation in Parkinson's disease: A virtual reality study. Parkinsonism Relat Disord. 2013 Aug;28. http://www.ncbi.nlm.nih.gov/pubmed/23993248
  2. Jones HE, Andolina IM, Ahmed B, Shipp SD, Clements JT, Grieve KL, Cudeiro J, Salt TE, Sillito AM. Differential feedback modulation of center and surround mechanisms in parvocellular cells in the visual thalamus. J Neurosci. 2012 Nov 7; 32(45):15946-51. http://www.ncbi.nlm.nih.gov/pubmed/23136432